The proteasome is a complex machinery in each cell which unfolds and breaks down proteins that are misfolded, damaged or no longer needed. The proteasome maturation protein (POMP) is essential [...]
Scientists from Norway and Switzerland uncovered for the first time a mutation in EPO, the gene encoding erythropoetin, as the genetic cause of an autosomal dominantly inherited form of [...]
During translation, a number of obstacles have the potential to arrest the ribosomal movement. In yeast, several studies revealed that the evolutionarily conserved Pelota (Pelo) recognizes [...]
An important role of the EDC4 gene in the intricate network regulating the repair of DNA damage and in cancer development has now been uncovered. In a study recently published in Nature [...]
Transforming growth factors beta (TGF-β) are vital in embryonic development and the regulation of many fundamental cellular functions in the human body. By binding and activating specific [...]
The 11th Molecular Biology of Hearing and Deafness Conference will be held from May 16th to 19th, 2018, at the Max Planck Institute of Biophysical Chemistry in Göttingen. This international [...]
Researchers of the University of Edinburgh have identified mutations in BRD4 as the disease-causing genetic defect in patients with a Cornelia-de-Lange-like condition and have thus provided new [...]
SELENBP1 has been reported to be involved in the development of several cancers, although its precise function has remained elusive until now. Now scientists have uncovered that autosomal [...]
As a transcription factor, the gene product of NFE2L2, the nuclear factor-erythroid 2-related factor 2 (NRF2), regulates the expression of a large number of genes including specifically various [...]
